When Is Mlb Opening Day 2025 Sf Giants. The giants are hosting the seattle mariners on april 4th, and they'll need some help getting the summer off to. Here's the san francisco giants schedule, including matchups, dates, times, and tv channels for the 2025 season.

The giants will open their 2025 home slate on april 4, when they’re set to host the mariners in a matinee matchup at oracle park. Here’s a look at the giants’ most notable dates: